With the tie perfectly poised, Rangers head to Spain looking to do what Philippe Clement did last season and return victorious.
The reins have been handed over to Barry Ferguson as the interim Rangers manager, but the aim is the same.
Rangers have a few injury concerns, however, Ferguson can still name a strong team.
The biggest decisions to be made will be in the forward line with Ernesto Valverde naming who he thinks will cause his Athletic Club side the most problems.
The Athletic boss could also be trying to play mind games with Ferguson though, given who he has named.

Ernesto Valverde names Rangers players who worry him
Speaking as part of the pre-match press conference, Valverde was asked to give his verdict on what sort of threat the visitors would pose:
“Rangers have a good formation, players who play well in the space.
“(Cyriel) Dessers is constantly running into the space, being a reference player, a beacon for his team. He’s a dangerous player.
“Their players from the outside are very well positioned, whether they’re playing James Tavernier in defence or in the midfield.
“Then they have (Vaclav) Cerny, who’s a bullet.
“He’s very precise when it comes to defining moments. He’s a player that in the space can hurt you.”
What decision is Ferguson going to make?
You would be hard pressed to find a Rangers fan who would pick Cyriel Dessers over Hamza Igamane.
There is a fundamental difference between Dessers and Igamane that makes the young Moroccan the more obvious choice.
For some reason though, Ferguson, like Valverde, seems to rate the more experienced Rangers No.9 and his place on the bench against Aberdeen suggests that he is set to start in the Estadio San Mames.
Dessers can be a difference maker, he can be clinical, he can cause teams problems, however, as seen against Dundee, he can also take 12 chances to score one.
If he scores the winner against Athletic, would anyone care this time how many chances it takes?
