The two sides played out an entertaining 2-2 draw at Ibrox eight days ago and will meet again at the Philips Stadion as the Gers look to make the Champions League Group Stages for the first time since 2010.
Holding the home advantage and with a talent strewn squad, PSV Eindhoven go into the match as favourites but Rangers have shown before just how capable they are on this stage.
With £40m on the line for the winner, as well as the prestige of Champions League competition, the pressure is mounting and here we predict the Rangers XI for the clash v PSV Eindhoven.
We expect Jon McLaughlin to continue in goals for the club with the keeper a shoo-in to start alongside James Tavernier and Connor Goldson in defence.
Borna Barisic is likely to get the left-back nod whilst injuries at centre-back – with the likes of Fil Helander, John Souttar and Ben Davies all out – meaning James Sands will continue in that left-sided centre-back slot.
In midfield, we expect John Lundstram to come in to the side and after being left out against Hibs amid rumours over his future, we’re tipping Glen Kamara to come in from the start in Eindhoven.
We expect Tom Lawrence to start this game with Malik Tillman coming back into the side after being rested against Hibs.
Ryan Kent is then likely to start out on the left with Antonio Colak continuing up front amid the ongoing controversy surrounding Alfredo Morelos.
Rangers predicted XI v PSV Eindhoven – 4-3-3
GK – Jon McLaughlin
DR – James Tavernier
DC – Connor Goldson
DC – James Sands
DL – Borna Barisic
CDM – John Lundstram
CM – Glen Kamara
CM – Tom Lawrence
RF – Malik Tillman
LF – Ryan Kent
ST – Antonio Colak